Søren Ditlefsen, Nikolaj Rud and Karen Christiansen finished their Masters degree and Rasmus Folino finished his Bachelor degree.

The administration’s planned cost reductions of DKK 100 million until 2019 are included in the overall financial plan for the university, which the board has just approved.

Fifteen employees had an exciting afternoon Friday, June 10, where they got to see the new Skou Building both inside and from above. Seats for the first tour for employees to the Skou Building was snapped up in under 30 minutes, and because of the great interest more opportunities to see the building is planned.

Small clinical trials have indicated that statins improve antidepressant treatment effects. We performed a register-based study including 872,216 individuals who initiated treatment with selective serotonin reuptake inhibitors (SSRIs). Individuals using SSRIs+statins were associated with a lower risk for hospitalization with depression, as compared to SSRIs alone, suggesting that concomitant treatment with SSRIs and statins may have better antidepressant treatment effects.

Several studies have suggested an important role of infections in the etiology of schizophrenia; however, shared genetic liability towards infections and schizophrenia could influence the association. We therefore investigated the possible effect of polygenic risk scores (PRS) for schizophrenia on the association between infections and the risk of schizophrenia utilizing the Danish registers combined with genetic information. We show that the PRS for schizophrenia and a history of infections have independent effects on the schizophrenia risk and that the PRS for schizophrenia did not influence the likelihood of getting an infection. While this study confirms the presence of a genetic risk for schizophrenia, we did not find evidence for a genetic liability to infections associated with the PRS. This does not necessarily imply that a genetic liability towards infections in people with schizophrenia is nonexistent but does suggest that it is distinct from the present PRS for schizophrenia.

Most GWAS are built on unrelated case-control studies, e.g. studies within the Psychiatric Genomics Consortium. In this paper we investigate the difference between the odds ratio, estimated using an unrelated case-control study, and the incidence rate ratio from longitudinal designs. From simulations we see that the odds ratio is not equal to the incidence rate ratio, and that these differences are reflected in the resulting p-values. The odds ratio measures the effect of the SNP on the probability of being diseased, whereas the incidence rate ratio measures the effect on the probability of becoming diseased.

Transcription factors and miRNAs regulate gene expression on pre- and post-transcriptional levels, respectively. They are known to have large interaction networks and play important roles in e.g. cell differentiation and tissue development. This study explores how several miRNAs and their abilities for regulating the expression of schizophrenia risk genes.

Transcription factors and miRNAs regulate gene expression on pre- and post-transcriptional levels, respectively. They are known to have large interaction networks and play important roles in e.g. cell differentiation and tissue development. This study explores the chromatin co-modifier, BRD1.