Genetic engineering is becoming a cornerstone method in molecular and cellular biology, biotechnology, biomedicine, and soon in the Hospital setting to treat genetic diseases and to genetically manipulate cells, e.g. immune cells, to endow them with better properties. This summer course will introduce state-of-the-art CRISPR/Cas systems and cover key applications in genetic engineering ranging from core gene editing applications to other capabilities of the system such as transcriptional and epigenetic regulation. The use of CRISPR/Cas for probing basic gene function will be described as well as the current status and future perspectives in therapeutic gene editing. The course will have a specific focus on enabling the students to independently design and perform CRISPR experiments, which will be supported by various theoretical exercises. These will cover aspects ranging from the initial design considerations to the final analysis of gene editing outcomes.
The course is specifically intended for students with a particular interest in biomedical research.
Exam info and full course description can be found in the course catalogue.
Please notice that this course is passed by active participation, and you will not receive a specific grade. Only pass/fail will appear on your transcript.
Course specific:
To apply for the course you must either be enrolled in a bachelor's degree, have a bachelor's degree or have passed a qualifying entry examination.
To be eligible for the course applicants should have passed Medical Genetics or an equivalent course at a different university with a curriculum encompassing basic genetics, structure and function of nucleic acids, and the central dogma of molecular biology. The course is a specialised course largely consisting of lectures and theoretical exercises. It has little to no overlap with other courses at Medicine or Molecular Medicine.
General:
Exchange Students: nomination from your home university
Freemovers: documentation for English Language proficiency
You can read more about the admission here.
