Deadline 11 Dec 23:59 CET
Expected start 1 Mar
Department of Animal and Veterinary Sciences - ANIVET Gut and host health (GHH) Blichers Allé 20 8830 Tjele
Fixed term full-time position 1 Mar 2024 - 31 May 2025 ID: 13572
The qualified candidate will become an essential member of a multidisciplinary team of international scientists based at the Group of Brain Development and Disease at the University of Copenhagen. The research group was established in 2017 and has a main research focus on the entorhinal cortex and its role in development, evolution, and Alzheimer’s disease. The teams’ strengths lie in stem cell biology, electrophysiology and single cell technologies.
This position is part of a Novo Nordisk Foundation Interdisciplinary Synergy grant. The overall research aim of the project is to produce a novel multiomic technology that combines spatial transcriptomics with electrophysiology for use in the neurosciences and includes collaborators from Harvard University/Brigham Women’s hospital and De Lille University, France.
The position entails profiling the entorhinal cortex (region of the brain) in mice using standard and novel multielectrode arrays and performing to a lesser extent, the spatial transcriptomics method, Merfish. This technique will be compared with a newly developed procedure in our lab, patch-seq, on the mouse entorhinal cortex. The applicant will also be expected to contribute to some elements of the patch-seq procedure.
The position involves a short stay at Harvard University, US, with a collaborating group to learn and perform Merfish.
The postdoc will:
- Perform mouse brain slice cultures and culture them in multielectrode arrays (MEAs).
- Establish novel methods for culturing murine brain slices in MEAs
- Perform brain slice cultures in novel MEAS produced in the NNF grant by collaborators.
- Fly to Boston, US, to perform merfish on SpaiCon arrays.
- Assist patch-seq experiments on mouse brain slices together with an employed postdoc.
Qualifications for a postdoc position
- Academic qualifications at PhD level in Neuroscience, Neurophysiology, Molecular Biomedicine or similar.
- Research experience in using multielectrode arrays
- Research experience in neuronal cell cultures.
- Research experience in working with and handling of mice.
- Knowledge and or experience in molecular biology techniques.
- Knowledge and or experience in single cell RNA sequencing and basic bioinformatics.
- Significant skills in data analyses of multielectrode array data
- Significant skills in scientific communication of research results
- The candidate must have excellent collaborative and English communication skills.
- The candidate must hold at least FELASA B certification (or equivalent animal experimentation course certification)
- Desirable experience and/or knowledge in spatial transcriptomic technologies
The project will contribute to the development of a new multiomic technology for the neurosciences which combines multielectrode arrays with spatial transcriptomics. The candidate will participate in knowledge exchange with society and industry.
Further information on the position may be obtained from Professor Vanessa Jane Hall from the research unit (Gut and host health), ph.. +45 35332512, email: email@example.com
Place of work and area of employmentThe place of work is mainly at the laboratory facilities at Department of Veterinary and Animal Sciences, University of Copenhagen, and the area of employment is Department of Animal and Veterinary Sciences, Blichers Allé 20, 8830 Tjele, AU Viborg, Aarhus University (AU) with related departments.
Shortlisting is used. This means that after the deadline for applications – and with the assistance from the assessment committee chairman, and the appointment committee if necessary, – the head of department selects the candidates to be evaluated. All applicants will be notified whether or not their applications have been sent to an expert assessment committee for evaluation. The selected applicants will be informed about the composition of the committee, and each applicant is given the opportunity to comment on the part of the assessment that concerns him/her self. Once the recruitment process is completed a final letter of rejection is sent to the deselected applicants.
If you want a referee to upload a letter of reference on your behalf, please state the referee’s contact information when you submit your application. We strongly recommend that you make an agreement with the person in question before you enter the referee’s contact information, and that you ensure that the referee has enough time to write the letter of reference before the application deadline.
Letter of reference
Unfortunately, it is not possible to ensure that letters of reference received after the application deadline will be taken into consideration.
Technical Sciences refers to the Ministerial Order on the Appointment of Academic Staff at Danish Universities under the Danish Ministry of Science, Technology and Innovation.
Formalities and salary range
The application must be in English and include a curriculum vitae, degree certificate, a complete list of publications, a statement of future research plans and information about research activities, teaching portfolio and verified information on previous teaching experience (if any). Guidelines for applicants can be found here.
Appointment shall be in accordance with the collective labour agreement between the Danish Ministry of Taxation and the Danish Confederation of Professional Associations. Further information on qualification requirements and job content may be found in the Memorandum on Job Structure for Academic Staff at Danish Universities.
Salary depends on seniority as agreed between the Danish Ministry of Taxation and the Confederation of Professional Associations.
Aarhus University’s ambition is to be an attractive and inspiring workplace for all and to foster a culture in which each individual has opportunities to thrive, achieve and develop. We view equality and diversity as assets, and we welcome all applicants.
Research activities will be evaluated in relation to actual research time. Thus, we encourage applicants to specify periods of leave without research activities, in order to be able to subtract these periods from the span of the scientific career during the evaluation of scientific productivity.
Aarhus University offers a broad variety of services for international researchers and accompanying families, including relocation service and career counselling to expat partners. Read more here. Please find more information about entering and working in Denmark here.
Aarhus University also offers a Junior Researcher Development Programme targeted at career development for postdocs at AU. You can read more about it here.
The application must be submitted via Aarhus University’s recruitment system, which can be accessed under the job advertisement on Aarhus University's website.
Questions about the position?
Vanessa Jane Hall Professor, Department of Animal and Veterinary Sciences - ANIVET Gut and host health (GHH) firstname.lastname@example.org
Questions about application and proces?
Nat-Tech Administrative Centre - Nat-Tech HR +4523357279 nat-tech.HR.email@example.com