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Department of Biomedicine - Forsk. & udd., Skou-bygningen - Faculty: Health

Postdoc in Stem Cell Biology and Regenerative Medicine

Deadline 5 Jul 23:59 CEST

Expected start 1 Sep

  • Department of Biomedicine - Forsk. & udd., Skou-bygningen Høegh-Guldbergs Gade 10 8000 Aarhus C

  • Fixed term full-time position 1 Sep 2022 - 31 Aug 2025 ID: 9323

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The Department of Biomedicine at Faculty of Health at Aarhus University invites applications for a position as Postdoc in the field of Stem Cell Biology and Regenerative Medicine, in the laboratory of Assistant Professor Dr. Ermelinda Porpiglia, as per 1 September 2022 or as soon as possible thereafter. The position is a full-time position for 3 years.

The department of Biomedicine prioritizes diversity and a good work environment, as this is a prerequisite for groundbreaking research. In a dynamic and international research environment, dedicated employees are looking to generate new knowledge within biomedical research areas such as infection and inflammation, membranes, neuroscience and personalized medicine. The Department of Biomedicine provides research-based teaching of the highest quality and is responsible for a large part of the medical degree program. Academic staff contribute to the teaching. English is the preferred language in the laboratory, at meetings and at seminars. The department employs approx. 500 people from all over the world, and they make use of the department's modern laboratory-, core- and animal facilities. The Department of Biomedicine focuses on innovation, entrepreneurship and collaboration with business and industry, and numerous researchers from the department have established companies to develop new medicinal treatments founded in strong scientific basic research. You can read more about the department here and about the faculty here.

About the research project

The laboratory of Assistant Professor Ermelinda Porpiglia is looking for a talented, ambitious and highly motivated postdoctoral fellow to investigate the role of the immune system in muscle regeneration and study, using single-cell technologies, the relationships between key immune cell types and muscle stem cells in aged skeletal muscle. The interdisciplinary research project will integrate cutting-edge single-cell proteomic approaches, such as single-cell mass cytometry (CyTOF) and imaging mass cytometry, with quantitative data analysis and dynamic modelling, to understand how unique interactions between immune cells and muscle stem cells orchestrate effective muscle regeneration and to identify the cellular interactions and signalling pathways that underlie impaired muscle regeneration in aging. This research will help us develop strategies to modulate the immune system to boost muscle tissue repair. More information about our research can be found here.

As a candidate for this full-time position, you will be expected to apply well-established CyTOF protocols and develop novel protocols for imaging mass cytometry, as well as leverage computational tools to address basic research questions in the area of muscle regeneration. This postdoctoral opportunity will enable training in cutting-edge experimental methods and bioinformatic pipelines for analysis of high-dimensional proteomic data. You will have the opportunity to participate in collaborative projects with multiple institutions from North America and Europe.

You should be self-driven and independent, with a track record of success supported by first-author publications in cell biology, immunology and/or systems biology. You should have a strong interest in stem cell biology and regenerative medicine. Ideally you are highly motivated, independent, an excellent communicator, and interested in working at the intersection between immunology and regenerative medicine.

Your job responsibilities

Based on our preliminary data you will develop your own project aimed to investigate the role of the immune system in muscle regeneration. You will collaborate with other members of the laboratory and with our core collaborators at the institute, and you will be expected to develop expertise in areas necessary for successful progress of your project. As Postdoc in Stem Cell Biology your position is primarily research-based but may also involve teaching assignments. You will contribute to the development of the department through research of high international quality. In your daily work, you will work closely with colleagues on your project, where you will receive supervision and guidance.

Your main tasks will consist of the following:
  • Designing and performing research studies
  • Performing high-throughput data analysis
  • Preparing figures and manuscripts
  • Applying for external fellowships
  • Contributing to grant applications
  • Supervising and training graduate students
  • Presenting work at internal, local, national and international meetings
  • Performing ongoing literature review to remain current with new procedures, computational tools and  related research
  • Proposing new research directions based on the advances discussed in literature
The work related to the project will take place at the Department of Biomedicine, and the successful candidate will be integrated into the department.

You will report to Assistant Professor Ermelinda Porpiglia.

Your competences
  • You hold a Ph.D. degree in cell biology, molecular biology, immunology, or closely related disciplines.
  • You have a scientific track-record of first-author peer reviewed publications and conference presentations, and a thorough understanding of stem cell biology or immunology.
  • You have experience with Flow Cytometry and Fluorescent Activated Cell Sorting (FACS)
  • You have experience with cell culture and primary cultures
  • You have experience with mouse handling and procedures, as well as mouse genetics
  • You have experience with immunofluorescence, immunohistochemistry and image processing software, such as ImageJ
  • Experience with single-cell technologies (CyTOF and single cell-RNA seq) is preferred but not required
  • You are goal-oriented, self-motivated and responsible
  • You have strong problem-solving skills and excellent organizational and project management skills
  • You have excellent verbal and written scientific communication skills (we expect you to be fluent in oral and written English).
  • You have good interpersonal skills and are able to work effectively in multidisciplinary and collaborative research environments
In order to be assessed as qualified for a Postdoc position, you must meet these academic criteria.

Shortlisting will be used.

Questions about the position

If you have any questions about the position, please contact Assistant Professor, Ermelinda Porpiglia, eporpiglia@biomed.au.dk, tel.: (+45) 42578870.

Your place of work will be the Department of Biomedicine, Høegh-Guldbergs Gade 10
8000 Aarhus C, Denmark.

We expect to conduct interviews in July.


Terms of employment


Application

Your application must include the following:
  • Motivated application
  • Curriculum Vitae
  • Diploma
  • Template for applicant - postdoc must be completed and uploaded under ‘Extra documents’
  • A list of publications
  • A teaching portfolio. We refer to Guideline on the use of teaching portfolios
  • A maximum of five of the publications of greatest relevance to the job may be submitted (optional)
  • Strategic research plan can be uploaded (optional)
  • Coauthor statement(s) can be uploaded (optional)
  • References/recommendations can be uploaded separately in the e-recruitment system (optional)
We refer to the faculty’s Guidelines for applicants.

The assessment committee may decide to include non-submitted material in its statement. In such cases, you will be informed and obliged to submit material, unless your application is withdrawn.

Aarhus University’s ambition is to be an attractive and inspiring workplace for all and to foster a culture in which each individual has opportunities to thrive, achieve and develop. We view equality and diversity as assets, and we welcome all applicants.

Letter of reference

If you want a referee to upload a letter of reference on your behalf, please state the referee’s contact information when you submit your application. We strongly recommend that you make an agreement with the person in question before you enter the referee’s contact information, and that you ensure that the referee has enough time to write the letter of reference before the application deadline.
Unfortunately, it is not possible to ensure that letters of reference received after the application deadline will be taken into consideration.


International applicant?

Aarhus University offers a broad variety of services for international researchers and accompanying families, including relocation service and career counselling to expat partners. Please find more information about entering and working in Denmark here. Aarhus University also has a Junior Researcher Development Programme. You can read more about it here.

The application must be submitted via Aarhus University’s recruitment system, which can be accessed under the job advertisement on Aarhus University's website.

Questions about the position?

Ermelinda Porpiglia Assistant Professor, Department of Biomedicine - Forskning og uddannelse, Skou-bygningen eporpiglia@biomed.au.dk

Questions about application and proces?

Health Administrative Centre - Health HR +4521623283 emply.he.hr@au.dk

Apply

Deadline: Tuesday 5 Jul 2022 at 23:59 CEST