Deadline 5 Jul 23:59 CEST
Expected start 1 Sep
Department of Biomedicine - Forsk. & udd., Skou-bygningen Høegh-Guldbergs Gade 10 8000 Aarhus C
Fixed term full-time position 1 Sep 2022 - 31 Aug 2025 ID: 9323
The department of Biomedicine prioritizes diversity and a good work environment, as this is a prerequisite for groundbreaking research. In a dynamic and international research environment, dedicated employees are looking to generate new knowledge within biomedical research areas such as infection and inflammation, membranes, neuroscience and personalized medicine. The Department of Biomedicine provides research-based teaching of the highest quality and is responsible for a large part of the medical degree program. Academic staff contribute to the teaching. English is the preferred language in the laboratory, at meetings and at seminars. The department employs approx. 500 people from all over the world, and they make use of the department's modern laboratory-, core- and animal facilities. The Department of Biomedicine focuses on innovation, entrepreneurship and collaboration with business and industry, and numerous researchers from the department have established companies to develop new medicinal treatments founded in strong scientific basic research. You can read more about the department here and about the faculty here.
About the research projectThe laboratory of Assistant Professor Ermelinda Porpiglia is looking for a talented, ambitious and highly motivated postdoctoral fellow to investigate the role of the immune system in muscle regeneration and study, using single-cell technologies, the relationships between key immune cell types and muscle stem cells in aged skeletal muscle. The interdisciplinary research project will integrate cutting-edge single-cell proteomic approaches, such as single-cell mass cytometry (CyTOF) and imaging mass cytometry, with quantitative data analysis and dynamic modelling, to understand how unique interactions between immune cells and muscle stem cells orchestrate effective muscle regeneration and to identify the cellular interactions and signalling pathways that underlie impaired muscle regeneration in aging. This research will help us develop strategies to modulate the immune system to boost muscle tissue repair. More information about our research can be found here.
As a candidate for this full-time position, you will be expected to apply well-established CyTOF protocols and develop novel protocols for imaging mass cytometry, as well as leverage computational tools to address basic research questions in the area of muscle regeneration. This postdoctoral opportunity will enable training in cutting-edge experimental methods and bioinformatic pipelines for analysis of high-dimensional proteomic data. You will have the opportunity to participate in collaborative projects with multiple institutions from North America and Europe.
You should be self-driven and independent, with a track record of success supported by first-author publications in cell biology, immunology and/or systems biology. You should have a strong interest in stem cell biology and regenerative medicine. Ideally you are highly motivated, independent, an excellent communicator, and interested in working at the intersection between immunology and regenerative medicine.
Your job responsibilitiesBased on our preliminary data you will develop your own project aimed to investigate the role of the immune system in muscle regeneration. You will collaborate with other members of the laboratory and with our core collaborators at the institute, and you will be expected to develop expertise in areas necessary for successful progress of your project. As Postdoc in Stem Cell Biology your position is primarily research-based but may also involve teaching assignments. You will contribute to the development of the department through research of high international quality. In your daily work, you will work closely with colleagues on your project, where you will receive supervision and guidance.
Your main tasks will consist of the following:
- Designing and performing research studies
- Performing high-throughput data analysis
- Preparing figures and manuscripts
- Applying for external fellowships
- Contributing to grant applications
- Supervising and training graduate students
- Presenting work at internal, local, national and international meetings
- Performing ongoing literature review to remain current with new procedures, computational tools and related research
- Proposing new research directions based on the advances discussed in literature
You will report to Assistant Professor Ermelinda Porpiglia.
- You hold a Ph.D. degree in cell biology, molecular biology, immunology, or closely related disciplines.
- You have a scientific track-record of first-author peer reviewed publications and conference presentations, and a thorough understanding of stem cell biology or immunology.
- You have experience with Flow Cytometry and Fluorescent Activated Cell Sorting (FACS)
- You have experience with cell culture and primary cultures
- You have experience with mouse handling and procedures, as well as mouse genetics
- You have experience with immunofluorescence, immunohistochemistry and image processing software, such as ImageJ
- Experience with single-cell technologies (CyTOF and single cell-RNA seq) is preferred but not required
- You are goal-oriented, self-motivated and responsible
- You have strong problem-solving skills and excellent organizational and project management skills
- You have excellent verbal and written scientific communication skills (we expect you to be fluent in oral and written English).
- You have good interpersonal skills and are able to work effectively in multidisciplinary and collaborative research environments
Shortlisting will be used.
Questions about the positionIf you have any questions about the position, please contact Assistant Professor, Ermelinda Porpiglia, firstname.lastname@example.org, tel.: (+45) 42578870.
Your place of work will be the Department of Biomedicine, Høegh-Guldbergs Gade 10
8000 Aarhus C, Denmark.
We expect to conduct interviews in July.
Terms of employment
- Appointment as a postdoc requires academic qualifications at PhD level.
- Further information on the appointment procedure can be found in the Ministerial Order on the Appointment of Academic Staff at Universities.
- The appointment is in accordance with the Danish Confederation of Professional Associations (Akademikerne).
- Remuneration is in accordance with the above, and the Salary agreement catalogue for staff at Health.
- The yearly base salary for a fulltime postdoc is between DKK 473.733,12 and DKK 527.059,29 depending on the years of working experience after achieved MSc degree. The base salary includes a position related supplement and pension (17.1 %). Additional supplement(s) for special qualifications can be negotiated. Authorisation supplemement(s) will be granted, if relevant for the position. Your local eligible trade union representative at Aarhus University negotiates your salary on your behalf.
- Researchers recruited from abroad are offered a special researcher tax scheme with a lower tax rate.
- Further information on qualification requirements and job description can be found in the Ministerial Order on Job Structure for Academic Staff
Your application must include the following:
- Motivated application
- Curriculum Vitae
- Template for applicant - postdoc must be completed and uploaded under ‘Extra documents’
- A list of publications
- A teaching portfolio. We refer to Guideline on the use of teaching portfolios
- A maximum of five of the publications of greatest relevance to the job may be submitted (optional)
- Strategic research plan can be uploaded (optional)
- Coauthor statement(s) can be uploaded (optional)
- References/recommendations can be uploaded separately in the e-recruitment system (optional)
The assessment committee may decide to include non-submitted material in its statement. In such cases, you will be informed and obliged to submit material, unless your application is withdrawn.
Aarhus University’s ambition is to be an attractive and inspiring workplace for all and to foster a culture in which each individual has opportunities to thrive, achieve and develop. We view equality and diversity as assets, and we welcome all applicants.
Letter of referenceIf you want a referee to upload a letter of reference on your behalf, please state the referee’s contact information when you submit your application. We strongly recommend that you make an agreement with the person in question before you enter the referee’s contact information, and that you ensure that the referee has enough time to write the letter of reference before the application deadline.
Unfortunately, it is not possible to ensure that letters of reference received after the application deadline will be taken into consideration.
Aarhus University offers a broad variety of services for international researchers and accompanying families, including relocation service and career counselling to expat partners. Please find more information about entering and working in Denmark here. Aarhus University also has a Junior Researcher Development Programme. You can read more about it here.
The application must be submitted via Aarhus University’s recruitment system, which can be accessed under the job advertisement on Aarhus University's website.
Questions about the position?
Ermelinda Porpiglia Assistant Professor, Department of Biomedicine - Forskning og uddannelse, Skou-bygningen email@example.com
Questions about application and proces?
Health Administrative Centre - Health HR +4521623283 firstname.lastname@example.org