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Department of Biomedicine - Forsk. & udd., Skou-bygningen - Faculty: Health

Postdoc in iPSC-models of AD

Deadline 30 Jan 23:59 CET

Expected start 1 Apr

  • Department of Biomedicine - Forsk. & udd., Skou-bygningen Høegh-Guldbergs Gade 10 8000 Aarhus C

  • Fixed term part-time position 1 Apr 2023 - 31 Mar 2025 18.5 hours per week ID: 11033

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The Department of Biomedicine at Faculty of Health at Aarhus University invites applications for a position as Postdoc in the field of SORL1-Associated Alzheimer’s Disease as per 1 April 2023 or as soon as possible thereafter. The position is a part-time position (18.5 hours/week) for 24 months  

The department of Biomedicine prioritises diversity and a good work environment, as this is a prerequisite for groundbreaking research. In a dynamic and international research environment, dedicated employees are looking to generate new knowledge within biomedical research areas such as infection and inflammation, membranes, neuroscience and personalised medicine. The Department of Biomedicine provides research-based teaching of the highest quality and is responsible for a large part of the medical degree programme. Academic staff contribute to the teaching. English is the preferred language in the laboratory, at meetings and at seminars. The department employs approx. 500 people from all over the world, and they make use of the department's modern laboratory-, core- and animal facilities. The Department of Biomedicine focuses on innovation, entrepreneurship and collaboration with business and industry, and numerous researchers from the department have established companies to develop new medicinal treatments founded in strong scientific basic research. You can read more about the department here and about the faculty here.

About the research project

The project involves generation of iPSC-models to study the role of SORL1 and understand the mechanism of pathogenic SORL1 variants.  Among the hundreds of known variants in the SORL1 gene, it is still not clear which are pathogenic, and the project aims to model some of the pathogenic variants in these cell-based systems on e.g., SORLA maturation and APP processing.

Your job responsibilities

As Postdoc in Alzheimer’s cell biology your position is primarily research-based but may also involve teaching assignments. You will contribute to the development of the department through research of high international quality. In your daily work, you will work closely with colleagues on your project, where you will receive supervision and guidance.
Your main tasks will consist of:
  • Independent research of high international quality, including publication.
  • Setting up methods in the Andersen lab and training of personal with these methods that the candidate will bring to the lab.
  • Generating cell models and characterization of their phenotypes related to Alzheimer’s disease, more specifically endolysosomal defects.
You will report to the Associate Professor Olav Andersen

Your competences

You have academic qualifications at PhD level, preferably within one or more of the following areas: Cell biology, Neurochemistry, or Biochemistry - with a focus on neurodegenerative processes. We request extensive prior experience with work on characterization of SORL1 variants and generation of human iPSC models. Experiences with confocal microscopy imaging and genome editing for cells are preferred.
As a person, you are ambitious, take ownership and possess good communication and interpersonal skills. We expect you to be fluent in oral and written English.
In order to be assessed as qualified for a Postdoc position, you must meet these academic criteria.

Shortlisting will be used.

Questions about the position

If you have any questions about the position, please contact Olav Andersen tel.: (+45) 2037 0740.

Your place of work will be the Department of Biomedicine, Høegh-Guldbergs Gade 10, DK-8000 Aarhus C, Denmark.

We expect to conduct interviews beginning of March 2023.

Terms of employment

Application

Your application must include the following:
  • Motivated application
  • Curriculum Vitae
  • Diploma
  • Template for applicant - postdoc
  • A list of publications
  • A teaching portfolio. We refer to Guideline on the use of teaching portfolios
  • A maximum of five of the publications of greatest relevance to the job may be submitted (optional)
  • Strategic research plan can be uploaded (optional)
  • Coauthor statement(s) can be uploaded (optional)
  • References/recommendations can be uploaded separately in the e-recruitment system (optional)
We refer to the faculty’s Guidelines for applicants.

The assessment committee may decide to include non-submitted material in its statement. In such cases, you will be informed and obliged to submit material, unless your application is withdrawn.

Aarhus University’s ambition is to be an attractive and inspiring workplace for all and to foster a culture in which each individual has opportunities to thrive, achieve and develop. We view equality and diversity as assets, and we welcome all applicants.

Letter of reference

If you want a referee to upload a letter of reference on your behalf, please state the referee’s contact information when you submit your application. We strongly recommend that you make an agreement with the person in question before you enter the referee’s contact information, and that you ensure that the referee has enough time to write the letter of reference before the application deadline.
Unfortunately, it is not possible to ensure that letters of reference received after the application deadline will be taken into consideration.

International applicant?

Aarhus University offers a broad variety of services for international researchers and accompanying families, including relocation service and career counselling to expat partners. Please find more information about entering and working in Denmark here. Aarhus University also has a Junior Researcher Development Programme. You can read more about it here.

The application must be submitted via Aarhus University’s recruitment system, which can be accessed under the job advertisement on Aarhus University's website.

Questions about the position?

Olav Michael Andersen

Olav Michael Andersen Associate Professor, Department of Biomedicine - Forskning og uddannelse, Skou-bygningen +4520370740 o.andersen@biomed.au.dk

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Deadline: Monday 30 Jan 2023 at 23:59 CET